Protein Variants | Comment | Organism |
---|---|---|
D1042N | the mutant exhibits an rhodamine 6G efflux rate that is 10% as high as that of the wild type | Saccharomyces cerevisiae |
S1368A | the mutant has wild type enzyme levels as well as wild type ATPase activity and transmembrane signaling | Saccharomyces cerevisiae |
S558Y | the mutation leads to markedly increased hypersensitivity towards all transport substrates | Saccharomyces cerevisiae |
V656A | the mutation leads to markedly increased hypersensitivity towards all transport substrates | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
beryllium fluoride | - |
Saccharomyces cerevisiae | |
clotrimazole | - |
Saccharomyces cerevisiae | |
vanadate | - |
Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Saccharomyces cerevisiae | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + xenobiotic/in | Saccharomyces cerevisiae | - |
ADP + phosphate + xenobiotic/out | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + clotrimazole/in | - |
Saccharomyces cerevisiae | ADP + phosphate + clotrimazole/out | - |
? | |
ATP + H2O + rhodamine 6G/in | - |
Saccharomyces cerevisiae | ADP + phosphate + rhodamine 6G/out | - |
? | |
ATP + H2O + xenobiotic/in | - |
Saccharomyces cerevisiae | ADP + phosphate + xenobiotic/out | - |
? | |
CTP + H2O + rhodamine 6G/in | low CTPase activity | Saccharomyces cerevisiae | CDP + phosphate + rhodamine 6G/out | - |
? | |
GTP + H2O + rhodamine 6G/in | - |
Saccharomyces cerevisiae | GDP + phosphate + rhodamine 6G/out | - |
? | |
UTP + H2O + rhodamine 6G/in | low UTPase activity | Saccharomyces cerevisiae | UDP + phosphate + rhodamine 6G/out | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDR5 | - |
Saccharomyces cerevisiae |