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Literature summary for 7.6.2.1 extracted from

  • Roland, B.; Graham, T.
    Decoding P4-ATPase substrate interactions (2016), Crit. Rev. Biochem. Mol. Biol., 51, 513-527 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
Saccharomyces cerevisiae 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + phospholipid[side 1] Saccharomyces cerevisiae
-
ADP + phosphate + phospholipid[side 2]
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + phosphatidylcholine[side 1]
-
Saccharomyces cerevisiae ADP + phosphate + phosphatidylcholine[side 2]
-
?
ATP + H2O + phosphatidylethanolamine[side 1]
-
Saccharomyces cerevisiae ADP + phosphate + phosphatidylethanolamine[side 2]
-
?
ATP + H2O + phospholipid[side 1]
-
Saccharomyces cerevisiae ADP + phosphate + phospholipid[side 2]
-
?

Synonyms

Synonyms Comment Organism
Dnf1
-
Saccharomyces cerevisiae
Dnf2
-
Saccharomyces cerevisiae
P4-ATPase
-
Saccharomyces cerevisiae
phospholipid flippase
-
Saccharomyces cerevisiae
PL flippase
-
Saccharomyces cerevisiae

General Information

General Information Comment Organism
metabolism the enzyme selectively transports glycerophospholipid species from the lumenal or exofacial aspect to the cytofacial leaflet, creating an asymmetric distribution of phospholipids across the membrane Saccharomyces cerevisiae