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Literature summary for 7.6.2.1 extracted from

  • Stevens, H.C.; Nichols, J.W.
    The proton electrochemical gradient across the plasma membrane of yeast is necessary for phospholipid flip (2007), J. Biol. Chem., 282, 17563-17567.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
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Saccharomyces cerevisiae 5886
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + phospholipid/in Saccharomyces cerevisiae Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast ADP + phosphate + phospholipid/out
-
?
ATP + H2O + phospholipid/in Saccharomyces cerevisiae LMY65 Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast ADP + phosphate + phospholipid/out
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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and strains LMY67, LMY69, and LMY94
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Saccharomyces cerevisiae LMY65
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and strains LMY67, LMY69, and LMY94
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + phospholipid/in Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast Saccharomyces cerevisiae ADP + phosphate + phospholipid/out
-
?
ATP + H2O + phospholipid/in ATP-dependent transport of phospholipids from outer to the inner monolayer of the cell membrane to maintain lipid asymmetry, usage of fluorescent labeled 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled, NBD-labeled, phospholipid substrate. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast Saccharomyces cerevisiae ADP + phosphate + phospholipid/out
-
?
ATP + H2O + phospholipid/in Dnf1p and Dnf2p are necessary for the internalization phospholipids across the plasma membrane of Saccharomyces cerevisiae, overview. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast Saccharomyces cerevisiae LMY65 ADP + phosphate + phospholipid/out
-
?
ATP + H2O + phospholipid/in ATP-dependent transport of phospholipids from outer to the inner monolayer of the cell membrane to maintain lipid asymmetry, usage of fluorescent labeled 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled, NBD-labeled, phospholipid substrate. ATP hydrolysis is not sufficient for phospholipid flip in the absence of the proton electrochemical gradient across the plasma membrane, the proton electrochemical gradient is required for phospholipid flip across the plasma membrane of yeast Saccharomyces cerevisiae LMY65 ADP + phosphate + phospholipid/out
-
?

Synonyms

Synonyms Comment Organism
Dnf1p and Dnf2p
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Saccharomyces cerevisiae
More the enzymes belong to the the P4 family of P-type ATPases Saccharomyces cerevisiae