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Literature summary for 7.4.2.8 extracted from

  • Schuch, R.; Naurelli, A.T.
    The Mxi-Spa type III secretory pathway of Shigella flexneri requires an outer membrane lipoprotein, MxiM, for invasion translocation (1999), Infect. Immun., 67, 1982-1991.
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
outer membrane the lipidated protein MxiM, required in type III secretion, is anchored to the inner leaflet of the outer membrane Shigella flexneri 19867
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Shigella flexneri invasion of epithelial cells by Shigella flexneri is mediated by a set of translocated bacterial invasins, the Ipa proteins, and its dedicated type III secretion system, Mxi-Spa ADP + phosphate
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 ?

Organism

Organism UniProt Comment Textmining
Shigella flexneri
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 type III secretion system
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Posttranslational Modification

Posttranslational Modification Comment Organism
lipoprotein the lipidated protein MxiM, required in type III secretion, is anchored to the inner leaflet of the outer membrane Shigella flexneri

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
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 Shigella flexneri ADP + phosphate
-
 ?
ATP + H2O invasion of epithelial cells by Shigella flexneri is mediated by a set of translocated bacterial invasins, the Ipa proteins, and its dedicated type III secretion system, Mxi-Spa Shigella flexneri ADP + phosphate
-
 ?

Subunits

Subunits Comment Organism
More the lipidated protein MxiM is required in type III secretion Shigella flexneri