Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.4.2.3 extracted from

  • Bhangoo, M.K.; Tzankov, S.; Fan, A.C.; Dejgaard, K.; Thomas, D.Y.; Young, J.C.
    Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import (2007), Mol. Biol. Cell, 18, 3414-3428.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.4.2.3

Activating Compound

Activating Compound Comment Organism Structure
Hsp40-related J domain protein DJA1
-
 Rattus norvegicus
Hsp40-related J domain protein DJA1
-
 Homo sapiens
Hsp40-related J domain protein DJA2
-
 Rattus norvegicus
Hsp40-related J domain protein DJA2
-
 Homo sapiens
Hsp40-related J domain protein DJA4
-
 Rattus norvegicus
Hsp40-related J domain protein DJA4
-
 Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
the sequence encoding human Hsc70 is inserted into the pProExHTa vector Homo sapiens
the sequence encoding rat Hsc70 is inserted into the pET11a vector Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial outer membrane
-
 Rattus norvegicus 5741
-
mitochondrial outer membrane
-
 Homo sapiens 5741
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70800
-
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Rattus norvegicus
-
 ADP + phosphate
-
 ir
ATP + H2O Homo sapiens
-
 ADP + phosphate
-
 ir

Organism

Organism UniProt Comment Textmining
Homo sapiens P11142
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
purified on nickel-Sepharose, by ion exchange on a Mono Q column, and by gel filtration Rattus norvegicus
purified on nickel-Sepharose, by ion exchange on a Mono Q column, and by gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Rattus norvegicus ADP + phosphate
-
 ir
ATP + H2O
-
 Homo sapiens ADP + phosphate
-
 ir

Synonyms

Synonyms Comment Organism
Hsc70 ATPase
-
 Rattus norvegicus
Hsc70 ATPase
-
 Homo sapiens
mitochondrial protein-transporting ATPase
-
 Rattus norvegicus
mitochondrial protein-transporting ATPase
-
 Homo sapiens
TOM protein complex
-
 Rattus norvegicus
TOM protein complex
-
 Homo sapiens
translocase of the mitochondrial outer membrane
-
 Rattus norvegicus
translocase of the mitochondrial outer membrane
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 ATPase activity assay Rattus norvegicus
30
-
 ATPase activity assay Homo sapiens