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Literature summary for 7.4.2.3 extracted from

  • DSilva, P.R.; Schilke, B.; Walter, W.; Craig, E.A.
    Role of Pam16s degenerate J domain in protein import across the mitochondrial inner membrane (2005), Proc. Natl. Acad. Sci. USA, 102, 12419-12424.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.4.2.3

Activating Compound

Activating Compound Comment Organism Structure
additional information Pam16 is unable to stimulate mtHsp70's ATPase activity Saccharomyces cerevisiae
Pam18 stimulates mtHsp70's ATPase activity, Pam18 is less active in complex with Pam16, which is not sufficient to have significant effects on mitochondrial protein import or cell growth Saccharomyces cerevisiae

Application

Application Comment Organism
additional information Pam16's J-like domain strongly interacts with Pam18's J domain, leading to a productive interaction of Pam18 with mtHsp70 at the import channel Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Synonyms

Synonyms Comment Organism
mitochondrial hsp70
-
 Saccharomyces cerevisiae
mtHSP70
-
 Saccharomyces cerevisiae