KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000496 | - |
L-cystine-[cystine-binding protein][side 1] | at pH 6.5 and 37°C | Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Escherichia coli | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + L-cystine-[cystine-binding protein][side 1] | Escherichia coli | - |
ADP + phosphate + L-cystine[side 2] + [cystine-binding protein][side 1] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + L-cystine-[cystine-binding protein][side 1] | - |
Escherichia coli | ADP + phosphate + L-cystine[side 2] + [cystine-binding protein][side 1] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FliY-YecSC | - |
Escherichia coli |
L-cystine transporter | - |
Escherichia coli |
Organism | Comment | Expression |
---|---|---|
Escherichia coli | enzyme expression is induced by H2O2 | up |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme imports L-cystine from the periplasm to the cytoplasm | Escherichia coli |
physiological function | the enzyme contributes to hydrogen peroxide tolerance. The L-cystine/L-cystine shuttle system plays a role of detoxification of hydrogen peroxide before lipid peroxidation occurs, and then specifically prevents damage to membrane lipids | Escherichia coli |