Literature summary for 7.4.2.12 extracted from

Vergauwen, B.; Verstraete, K.; Senadheera, D.B.; Dansercoer, A.; Cvitkovitch, D.G.; Guedon, E.; Savvides, S.N.
Molecular and structural basis of glutathione import in Gram-positive bacteria via GshT and the cystine ABC importer TcyBC of Streptococcus mutans (2013), Mol. Microbiol., 89, 288-303 .

Search for more literature for 7.4.2.12

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Streptococcus mutans	16020	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + L-cystine-[cystine-binding protein TcyA](side 1)	Streptococcus mutans	-	ADP + phosphate + L-cystine(side 2) + [cystine-binding protein TcyA](side 1)	-	?
ATP + H2O + L-cystine-[cystine-binding protein TcyA](side 1)	Streptococcus mutans UA159	-	ADP + phosphate + L-cystine(side 2) + [cystine-binding protein TcyA](side 1)	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptococcus mutans	-	-	-
Streptococcus mutans UA159	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + L-cystine-[cystine-binding protein TcyA](side 1)	-	Streptococcus mutans	ADP + phosphate + L-cystine(side 2) + [cystine-binding protein TcyA](side 1)	-	?
ATP + H2O + L-cystine-[cystine-binding protein TcyA](side 1)	-	Streptococcus mutans UA159	ADP + phosphate + L-cystine(side 2) + [cystine-binding protein TcyA](side 1)	-	?

Synonyms

Synonyms	Comment	Organism
cystine ABC importer	-	Streptococcus mutans
cystine-specific ABC transporter	-	Streptococcus mutans
tcyABC	-	Streptococcus mutans
TcyB	transmembrane permease component	Streptococcus mutans
TcyC	ATPase component	Streptococcus mutans

General Information

General Information	Comment	Organism
physiological function	the enzyme is required for growth of Streptococcus mutans on glutathione as the sole source of sulfur	Streptococcus mutans

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)