Protein Variants | Comment | Organism |
---|---|---|
additional information | overexpression of LHT1 in Arabidopsis thaliana results in increased uptake, with uptake rates of between 219 and 456% of wild-type uptake, and saturating kinetics for L-Gln and increased but linear kinetics for L-Ala, L-Asp and L-Glu, in comparison to the wild-type plant. In the LHT1 mutant, uptake of L-Gln, L-Ala, L-Glu and L-Asp is greatly reduced by on average 61-85% over the entire concentration range, while the uptake of L-Arg and L-Lys is unaffected. AAP1 mutants do not display any major differences in the uptake of any of the amino acids tested | Arabidopsis thaliana |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.041 | - |
L-glutamine/out | wild-type LHT1, pH 5.8, temperature not specified in the publication | Arabidopsis thaliana |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Arabidopsis thaliana Col-0 | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | - |
Arabidopsis thaliana | - |
shoot | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + L-alanine/out | - |
Arabidopsis thaliana | ADP + phosphate + L-alanine/in | - |
? | |
ATP + H2O + L-alanine/out | - |
Arabidopsis thaliana Col-0 | ADP + phosphate + L-alanine/in | - |
? | |
ATP + H2O + L-aspartate/out | - |
Arabidopsis thaliana | ADP + phosphate + L-aspartate/in | - |
? | |
ATP + H2O + L-aspartate/out | - |
Arabidopsis thaliana Col-0 | ADP + phosphate + L-aspartate/in | - |
? | |
ATP + H2O + L-glutamate/out | - |
Arabidopsis thaliana | ADP + phosphate + L-glutamate/in | - |
? | |
ATP + H2O + L-glutamate/out | - |
Arabidopsis thaliana Col-0 | ADP + phosphate + L-glutamate/in | - |
? | |
ATP + H2O + L-glutamine/out | - |
Arabidopsis thaliana | ADP + phosphate + glutamine/in | - |
? | |
ATP + H2O + L-histidine/out | - |
Arabidopsis thaliana | ADP + phosphate + L-histidine/in | - |
? | |
ATP + H2O + L-histidine/out | - |
Arabidopsis thaliana Col-0 | ADP + phosphate + L-histidine/in | - |
? | |
ATP + H2O + neutral amino acid/out | - |
Arabidopsis thaliana | ADP + phosphate + neutral amino acid/in | - |
? | |
additional information | LHT1 displays high affinity for neutral amino acids, L-His, and acidic amino acids. Amino acid permease 1 mediates uptake of several neutral amino acids as well as L-Glu and L-His but, similar to LHT1, activity for L-Arg and L-Lys is not detected | Arabidopsis thaliana | ? | - |
? | |
additional information | LHT1 displays high affinity for neutral amino acids, L-His, and acidic amino acids. Amino acid permease 1 mediates uptake of several neutral amino acids as well as L-Glu and L-His but, similar to LHT1, activity for L-Arg and L-Lys is not detected | Arabidopsis thaliana Col-0 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AAP1 | - |
Arabidopsis thaliana |
amino acid permease 1 | - |
Arabidopsis thaliana |
LHT1 | - |
Arabidopsis thaliana |
lysine histidine transporter 1 | - |
Arabidopsis thaliana |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.8 | - |
assay at | Arabidopsis thaliana |