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Literature summary for 7.2.4.4 extracted from
- The malonate decarboxylase enzyme system of Malonomonas rubra: evidence for the cytoplasmic location of the biotin-containing component (1993), Arch. Microbiol., 160, 126-131.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Avidin | inhibition can be partially reversed with an excess of biotin | Malonomonas rubra |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | enzyme system involving cytoplasmic and membrane components | Propionigenium modestum | 5737 | - |
| cytoplasm | enzyme system involving cytoplasmic and membrane components | Malonomonas rubra | 5737 | - |
| membrane | enzyme system involving cytoplasmic and membrane components | Propionigenium modestum | 16020 | - |
| membrane | enzyme system involving cytoplasmic and membrane components | Malonomonas rubra | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Malonomonas rubra | - |
- |
- |
| Propionigenium modestum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| isolation of the biotinyl protein from the complex in catalytically inactive form in presence of detergent | Malonomonas rubra |
Renatured (Commentary)
| Renatured (Comment) | Organism |
|---|---|
| inhibition of malonate decarboxylase complex by avidin can be partially reversed with an excess of biotin | Malonomonas rubra |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| biotin | enzyme complex contains a single biotinyl protein of 120000 Dalton in the cell membrane | Propionigenium modestum |  |
| biotin | enzyme complex contains a single biotinyl protein of 120000 Dalton in the cytoplasm | Malonomonas rubra | |
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