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Literature summary for 7.2.2.9 extracted from

  • Lai, H.; Sun, C.; Tang, H.; Fan, X.; Ma, Y.; Li, Y.
    Functional characterization of the copper-transporting P-type ATPase gene of Penicillium janthinellum strain GXCR (2009), J. Microbiol., 47, 736-745.
    View publication on PubMed
Search for more literature for 7.2.2.9

Cloned(Commentary)

Cloned (Comment) Organism
gene pcpA, cDNA and amino acid sequence determination and analysis, quantitative real-time PCR expression analysis and sequence comparison, overview Penicillium janthinellum

Protein Variants

Protein Variants Comment Organism
additional information gene pcpA silencing using RNA interference in strain GXCR leads to reduced PcpA activity and increased sensitivity of the mutant organism to Cu2+, Cd2+, Fe2+, and Ag+ compared to the wild-type, phenotype, overview Penicillium janthinellum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Cu2+/in Penicillium janthinellum
-
 ADP + phosphate + Cu2+/out
-
 ?
ATP + H2O + Cu2+/in Penicillium janthinellum GXCR
-
 ADP + phosphate + Cu2+/out
-
 ?

Organism

Organism UniProt Comment Textmining
Penicillium janthinellum A7X9R7 gene pcpA
-
Penicillium janthinellum GXCR A7X9R7 gene pcpA
-

Source Tissue

Source Tissue Comment Organism Textmining
conidium
-
 Penicillium janthinellum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Cu2+/in
-
 Penicillium janthinellum ADP + phosphate + Cu2+/out
-
 ?
ATP + H2O + Cu2+/in
-
 Penicillium janthinellum GXCR ADP + phosphate + Cu2+/out
-
 ?

Subunits

Subunits Comment Organism
More PcpA comtains a heavy-metal-associated domain, a P-type ATPase domain, and a haloacid dehalogenase-like hydrolase domain Penicillium janthinellum

Synonyms

Synonyms Comment Organism
copper-transporting P-type ATPase
-
 Penicillium janthinellum
CtpA
-
 Penicillium janthinellum
PcpA
-
 Penicillium janthinellum

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Penicillium janthinellum