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Literature summary for 7.2.2.9 extracted from
- Structural and functional insights of Wilson disease copper-transporting ATPase (2002), J. Bioenerg. Biomembr., 34, 339-349.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi trans face | - |
Homo sapiens | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | six binding sites, may be reduced to Cu+ upon binding, copper binding is cooperative and induces conformational changes in the enzyme | Homo sapiens |  |
| Zn2+ | zinc binding sites are different than copper binding sites | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + Cu2+/in | - |
Homo sapiens | ADP + phosphate + Cu2+/out | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ATP7B | - |
Homo sapiens |
| Wilson's disease copper-transporting ATPase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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