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Literature summary for 7.2.2.5 extracted from

  • Bartsevich, V.V.; Pakrasi, H.B.
    Manganese transport in the cyanobacterium Synechocystis sp. PCC 6803 (1996), J. Biol. Chem., 271, 26057-26061.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information gene replacements Synechocystis sp.

Inhibitors

Inhibitors Comment Organism Structure
Cd2+ Ki: 0.004-0.008 mM, competitive inhibition Synechocystis sp.
Co2+ Ki: 0.008-0.015 mM, competitive inhibition Synechocystis sp.
additional information no inhibition by Fe2+ Synechocystis sp.
Zn2+ Ki: 0.008-0.015 mM, competitive inhibition Synechocystis sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1 3 Mn2+
-
Synechocystis sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane MntB Synechocystis sp. 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28700
-
protein encoded by mntA, amino acid sequence Synechocystis sp.
33400
-
protein encoded by mntB, amino acid sequence Synechocystis sp.
36100
-
protein encoded by mntC, amino acid sequence Synechocystis sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Mn2+/out Synechocystis sp.
-
ADP + phosphate + Mn2+/in
-
?

Organism

Organism UniProt Comment Textmining
Synechocystis sp.
-
strain PCC 6803
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Mn2+/out
-
Synechocystis sp. ADP + phosphate + Mn2+/in
-
?

Subunits

Subunits Comment Organism
More ABC-transporter Synechocystis sp.
More transporter called MntABC, encoded by mntCAB operon Synechocystis sp.

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.004 0.008 Cd2+ competitive inhibition Synechocystis sp.
0.008 0.015 Co2+ competitive inhibition Synechocystis sp.