Literature summary for 7.2.2.5 extracted from

Jakubovics, N.S.; Smith, A.W.; Jenkinson, H.F.
Expression of the virulence-related sca (Mn2+) permease in Streptococcus gordonii is regulated by a diphtheria toxin metallorepressor-like protein scaR (2000), Mol. Microbiol., 38, 140-153.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + Mn2+/out	Streptococcus gordonii	-	ADP + phosphate + Mn2+/in	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptococcus gordonii	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Mn2+/out	-	Streptococcus gordonii	ADP + phosphate + Mn2+/in	-	?

Subunits

Subunits	Comment	Organism
More	ABC-transporter	Streptococcus gordonii
More	sca transcription is regulated by ScaR in response to available Mn2+	Streptococcus gordonii
More	Sca transporter high affinity for Mn2+, but may also transport Zn2+	Streptococcus gordonii

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Release 2023.1 (January 2023)