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Literature summary for 7.2.2.5 extracted from

  • Kolenbrander, P.E.; Andersen, R.N.; Baker, R.A.; Jenkinson, H.F.
    The adhesion-associated sca operon in Streptococcus gordonii encodes an inducible high-affinity ABC transporter for Mn2+ uptake (1998), J. Bacteriol., 180, 290-295.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.5

Inhibitors

Inhibitors Comment Organism Structure
Zn2+ Sca, inhibits Mn2+ uptake Streptococcus gordonii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1 0.3 Mn2+ uptake of Mn2+ by wild type cells Streptococcus gordonii

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane encoded by scaB, transmembrane Streptococcus gordonii 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Mn2+/out Streptococcus gordonii
-
 ADP + phosphate + Mn2+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus gordonii
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
lipoprotein encoded by scaA Streptococcus gordonii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Mn2+/out
-
 Streptococcus gordonii ADP + phosphate + Mn2+/in
-
 ?

Subunits

Subunits Comment Organism
More ABC-transporter Streptococcus gordonii
More components involved are encoded by scaC (ATP-binding), scaA (substrate binding), scaB Streptococcus gordonii