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Literature summary for 7.2.2.2 extracted from

  • Jasinski, M.; Sudre, D.; Schansker, G.; Schellenberg, M.; Constant, S.; Martinoia, E.; Bovet, L.
    AtOSA1, a member of the Abc1-like family, as a new factor in cadmium and oxidative stress response (2008), Plant Physiol., 147, 719-731.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.2

Cloned(Commentary)

Cloned (Comment) Organism
OSA1 expression analysis, and phylogenetic analysis, overview. No complementation of Saccharomyces cerevisiae mutant strain W303-1A abc1THIS3 by the wild-type enzyme Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information despite sharing homology to the mitochondrial ABC1 of Saccharomyces cerevisiae, Arabidopsius thaliana OSA1 is not able to complement yeast strains deleted in the endogenous ABC1 gene. The atosa1-1 and atosa1-2 T-DNA insertion mutants are more affected than wild-type plants by Cd2+ and reveal an increased sensitivity toward oxidative stress caused by hydrogen peroxide and highlight. The mutants exhibit higher superoxide dismutase activities and differences in the expression of genes involved in the antioxidant pathway, phernotype, overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast envelope membrane Arabidopsis thaliana 9507
-
membrane
-
 Arabidopsis thaliana 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
 x * 70000 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Cd2+/in Arabidopsis thaliana chloroplast envelope membrane protein OSA1, a member of the Abc1-like family, acts as a factor in cadmium and oxidative stress response, playing a role in the balance of oxidative stress ADP + phosphate + Cd2+/out
-
 ?
additional information Arabidopsis thaliana in the absence of Cd21, an increase in the expression of AtOSA1 is correlated with plant aging. The transcript level of AtOSA1, which is age dependent, is also down-regulated in the night, circadian rhythm dependencies, and senescent leaves ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q0WLU3 ecotype Col-0
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
 Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
flower
-
 Arabidopsis thaliana
-
leaf high expression level Arabidopsis thaliana
-
additional information poor expression in roots Arabidopsis thaliana
-
stem low expression level Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Cd2+/in
-
 Arabidopsis thaliana ADP + phosphate + Cd2+/out
-
 ?
ATP + H2O + Cd2+/in chloroplast envelope membrane protein OSA1, a member of the Abc1-like family, acts as a factor in cadmium and oxidative stress response, playing a role in the balance of oxidative stress Arabidopsis thaliana ADP + phosphate + Cd2+/out
-
 ?
additional information in the absence of Cd21, an increase in the expression of AtOSA1 is correlated with plant aging. The transcript level of AtOSA1, which is age dependent, is also down-regulated in the night, circadian rhythm dependencies, and senescent leaves Arabidopsis thaliana ?
-
 ?

Subunits

Subunits Comment Organism
? x * 70000 Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
More the enzyme is a member of the Abc1-like family Arabidopsis thaliana
OSA1
-
 Arabidopsis thaliana
oxidative stress-related Abc1-like protein
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Arabidopsis thaliana