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Literature summary for 7.2.2.2 extracted from

  • Preveral, S.; Ansoborlo, E.; Mari, S.; Vavasseur, A.; Forestier, C.
    Metal(loid)s and radionuclides cytotoxicity in Saccharomyces cerevisiae. Role of YCF1, glutathione and effect of buthionine sulfoximine (2006), Biochimie, 88, 1651-1663.
    View publication on PubMed

Application

Application Comment Organism
environmental protection overexpression of this fungal transporter in plants can be useful for phytoremediation of lead and cadmium polluted soils Saccharomyces cerevisiae

Cloned(Commentary)

Cloned (Comment) Organism
the pYES2 plasmid is used for overexpression of EGFP-N2, YCF1, or YCF-EGFP-N2 in different Saccharomyces cerevisiae strains Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
vacuolar membrane
-
Saccharomyces cerevisiae 5774
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Cd2+/in Saccharomyces cerevisiae transports glutathione-S-conjugates, like Cd-GS2, from the cytosol into the vacuole ADP + phosphate + Cd2+/out
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Cd2+/in transports glutathione-S-conjugates, like Cd-GS2, from the cytosol into the vacuole Saccharomyces cerevisiae ADP + phosphate + Cd2+/out
-
?

Synonyms

Synonyms Comment Organism
cadmium-transporting ATPase
-
Saccharomyces cerevisiae
Ycf1
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Saccharomyces cerevisiae