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Literature summary for 7.2.2.13 extracted from

  • Thundathil, J.C.; Rajamanickam, G.D.; Kastelic, J.P.; Newton, L.D.
    The effects of increased testicular temperature on testis-specific isoform of Na+/K+ -ATPase in sperm and its role in spermatogenesis and sperm function (2012), Reprod. Domest. Anim., 47 Suppl 4, 170-177.
    View publication on PubMed
Search for more literature for 7.2.2.13

Inhibitors

Inhibitors Comment Organism Structure
Ouabain
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Bos taurus 5886
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
112000
-
 1 * 112000 + 1 * 35000-60000 Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + 3 Na+/in + 2 K+/out Bos taurus
-
 ADP + phosphate + 3 Na+/out + 2 K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
sperm
-
 Bos taurus
-
testis
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + 3 Na+/in + 2 K+/out
-
 Bos taurus ADP + phosphate + 3 Na+/out + 2 K+/in
-
 ?

Subunits

Subunits Comment Organism
heterodimer 1 * 112000 + 1 * 35000-60000 Bos taurus

Synonyms

Synonyms Comment Organism
Na+/K+-ATPase
-
 Bos taurus

General Information

General Information Comment Organism
physiological function in addition to its role as a sodium pump regulating sperm motility, Na+/K+-ATPase is also involved as a signalling molecule during sperm capacitation Bos taurus