Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Na+/in + K+/out | Drosophila melanogaster | - |
ADP + phosphate + Na+/out + K+/in | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Johnston's organ | - |
Drosophila melanogaster | - |
scolopale cell | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Na+/in + K+/out | - |
Drosophila melanogaster | ADP + phosphate + Na+/out + K+/in | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ATPalpha | catalytic subunit | Drosophila melanogaster |
Na pump | - |
Drosophila melanogaster |
Na+/K+-ATPase | - |
Drosophila melanogaster |
General Information | Comment | Organism |
---|---|---|
malfunction | knocking down of catalytic subunit ATPalpha, but not alpha-like, in the entire Johnston's organ results in complete deafness. Knocking down beta subunit nrv2 in scolopale cells reduces ATPalpha expression in scolopale cells and causes almost complete deafness | Drosophila melanogaster |
physiological function | the catalytic subunit ATPalpha is required for hearing | Drosophila melanogaster |