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Literature summary for 7.2.2.13 extracted from

  • Franca, J.L.; Pinto, M.R.; Lucena, M.N.; Garcon, D.P.; Valenti, W.C.; McNamara, J.C.; Leone, F.A.
    Subcellular localization and kinetic characterization of a gill (Na+, K+)-ATPase from the giant freshwater prawn Macrobrachium rosenbergii (2013), J. Membr. Biol., 246, 529-543.
    View publication on PubMed
Search for more literature for 7.2.2.13

Inhibitors

Inhibitors Comment Organism Structure
additional information enzyme activity is inhibited by excess ATP Macrobrachium rosenbergii
orthovanadate up to 75% inhibition at 0.05 mM Macrobrachium rosenbergii
Ouabain 73% inhibition at 3 mM Macrobrachium rosenbergii

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Macrobrachium rosenbergii
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
K+ K+ and NH4+ (1-20 mM each) synergistically stimulate enzyme activity (about 25%) Macrobrachium rosenbergii
NH4+ K+ and NH4+ (1-20 mM each) synergistically stimulate enzyme activity (about 25%) Macrobrachium rosenbergii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
108000
-
 x * 108000, alpha subunit, SDS-PAGE Macrobrachium rosenbergii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Na+/in + K+/out Macrobrachium rosenbergii
-
 ADP + phosphate + Na+/out + K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Macrobrachium rosenbergii
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gill
-
 Macrobrachium rosenbergii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+/in + K+/out
-
 Macrobrachium rosenbergii ADP + phosphate + Na+/out + K+/in
-
 ?

Subunits

Subunits Comment Organism
? x * 108000, alpha subunit, SDS-PAGE Macrobrachium rosenbergii

Synonyms

Synonyms Comment Organism
(Na+, K+)-ATPase
-
 Macrobrachium rosenbergii

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0002
-
 orthovanadate at pH 7.4 and 25°C Macrobrachium rosenbergii
0.0124
-
 Ouabain at pH 7.4 and 25°C Macrobrachium rosenbergii