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Literature summary for 7.2.2.13 extracted from

  • Petrovic, V.; Colovic, M.; Krstic, D.; Vujacic, A.; Petrovic, S.; Joksic, G.; Bugarcic, A.; Vasic, V.
    In vitro effects of some gold complexes on Na+/K+ ATPase activity and cell proliferation (2013), J. Inorg. Biochem., 124, 35-41.
    View publication on PubMed
Search for more literature for 7.2.2.13

Inhibitors

Inhibitors Comment Organism Structure
AuCl4-
-
 Sus scrofa
[Au(2,2'-bipyridine)Cl2]+
-
 Sus scrofa
[Au(dimethylsulfoxide)2Cl2]+
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Sus scrofa 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Na+/in + K+/out Sus scrofa
-
 ADP + phosphate + Na+/out + K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain cortex
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+/in + K+/out
-
 Sus scrofa ADP + phosphate + Na+/out + K+/in
-
 ?

Synonyms

Synonyms Comment Organism
Na+,K+-ATPase
-
 Sus scrofa
sodium potassium adenosinetriphosphatase
-
 Sus scrofa

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000575
-
 at pH 7.4 and 37°C Sus scrofa AuCl4-
0.0055
-
 at pH 7.4 and 37°C Sus scrofa [Au(dimethylsulfoxide)2Cl2]+
0.0398
-
 at pH 7.4 and 37°C Sus scrofa [Au(2,2'-bipyridine)Cl2]+