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Literature summary for 7.2.2.13 extracted from

  • Ghosh, B.; Chakraborti, T.; Kar, P.; Dey, K.; Chakraborti, S.
    Solubilization, purification, and reconstitution of alpha 2 beta 1 isozyme of Na+/K+ -ATPase from caveolae of pulmonary smooth muscle plasma membrane: comparative studies with DHPC, C12E8, and Triton X-100 (2009), Mol. Cell. Biochem., 323, 169-184.
    View publication on PubMed
Search for more literature for 7.2.2.13

Inhibitors

Inhibitors Comment Organism Structure
Ouabain
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Bos taurus 5886
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 1 * 110000 + 1 * 45000, alpha2 + beta1 Bos taurus
110000
-
 1 * 110000 + 1 * 45000, alpha2 + beta1 Bos taurus
155000
-
 non-denaturing PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
reconstitution with phospholipid dioleoyl-phosphatidylcholine Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
muscle pulmonary artery smooth muscle Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
11.96
-
-
 Bos taurus
19.84
-
 in reconstituted vesicles Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+/in + K+/out
-
 Bos taurus ADP + phosphate + Na+/out + K+/in
-
 ?

Subunits

Subunits Comment Organism
heterodimer 1 * 110000 + 1 * 45000, alpha2 + beta1 Bos taurus

Synonyms

Synonyms Comment Organism
Na+-K+-ATPase alpha1-beta1 isoenzyme Bos taurus
Na+-K+-ATPase alpha2-beta1 isoenzyme Bos taurus