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Literature summary for 7.2.2.13 extracted from

  • Reyes, N.; Gadsby, D.C.
    Ion permeation through the Na+,K+-ATPase (2006), Nature, 443, 470-474.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Xenopus laevis Xenopus laevis

Protein Variants

Protein Variants Comment Organism
D813C decrease in cation/anion selectivity, which is grossly impaired after treatment with 2-trimethylammonium-ethyl-methanethiosulphonate Xenopus laevis
D817C highly cation-selective pump-channel, no response to modification by 2-trimethylammonium-ethyl-methanethiosulphonate Xenopus laevis
E321C reaction with 2-trimethylammonium-ethyl-methanethiosulphonate does not decrease cation current Xenopus laevis
E336C decrease in cation/anion selectivity, which is transformed from cation-selective to anoin-selective after treatment with 2-trimethylammonium-ethyl-methanethiosulphonate Xenopus laevis
E788C highly cation-selective pump-channel, no response to modification by 2-trimethylammonium-ethyl-methanethiosulphonate Xenopus laevis
G805C reaction with 2-trimethylammonium-ethyl-methanethiosulphonate or with 2-aminocarbonyl-ethyl-methanethiosulphonate does not decrease cation current Xenopus laevis
N785C highly cation-selective pump-channel, no response to modification by 2-trimethylammonium-ethyl-methanethiosulphonate Xenopus laevis
T806C cation current is diminished after reaction with 2-trimethylammonium-ethyl-methanethiosulphonat and 7fold decreased after reaction with 2-aminocarbonyl-ethyl-methanethiosulphonate Xenopus laevis

Organism

Organism UniProt Comment Textmining
Xenopus laevis
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