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Literature summary for 7.2.2.13 extracted from

  • Li, T.; Roer, R.; Vana, M.; Pate, S.; Check, J.
    Gill area, permeability and Na+,K+ -ATPase activity as a function of size and salinity in the blue crab, Callinectes sapidus (2006), J. Exp. Zool. A, 305, 233-245.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Ouabain
-
Callinectes sapidus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
8.6
-
Na+/in posterior gill, juvenile crab acclimated to dilute seawater of 150 mOsm, pH 7.4 Callinectes sapidus
21.3
-
Na+/in anterior gill, sub-adult crab acclimated to dilute seawater of 150 mOsm, pH 7.4 Callinectes sapidus

Organism

Organism UniProt Comment Textmining
Callinectes sapidus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gill acclimation to dilute seawater induces increased expression of Na+K+-ATPase and enzyme activity, with the increase being less in juveniles than in larger crabs. Juveniles maintain osmotic and ionic homeostasis by the expression and utilization of extremely high levels of gill Na+K+ATPase, in posterior, as well in anterior, gills Callinectes sapidus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Na+/in
-
Callinectes sapidus ADP + phosphate + Na+/out
-
?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.4
-
pH 7.4 Callinectes sapidus Ouabain