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Literature summary for 7.2.2.13 extracted from
- Beta-subunit of cardiac Na+-K+-ATPase dictates the concentration of the functional enzyme in caveolae (2006), Am. J. Physiol. Cell Physiol., 291, C569-C578.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Na2CO3 | inactivation | Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endosome | uneven distribution of alpha1 and beta1 subunits in early and late endosome suggesting different internalization routes | Rattus norvegicus | 5768 | - |
| membrane | light caveolar membranes contain 30-40% of alpha1 subunits and 80-90% of beta1 subunits. Subunits are associated with caveolin oligomers | Rattus norvegicus | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| treatment of membranes by KCl leaves the enzyme intact, while Na2CO3 is inactivating | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| myocyte | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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