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Literature summary for 7.2.2.13 extracted from

  • Petrushanko, I.; Bogdanov, N.; Bulygina, E.; Grenacher, B.; Leinsoo, T.; Boldyrev, A.; Gassmann, M.; Bogdanova, A.
    Na-K-ATPase in rat cerebellar granule cells is redox sensitive (2006), Am. J. Physiol. Regul. Integr. Comp. Physiol., 290, R916-925.
    View publication on PubMed
Search for more literature for 7.2.2.13

Activating Compound

Activating Compound Comment Organism Structure
1-chloro-2,4-dinitrobenzene increase of the hydrolytic activity of the Na/K ATPase Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
1-chloro-2,4-dinitrobenzene inhibition of the transport activity of the Na-K pump Rattus norvegicus
ethylester of glutathione inhibition of the transport activity of the Na-K pump Rattus norvegicus
Ouabain
-
 Rattus norvegicus
reduced glutathione extracellular and, or intracellular, inhibition of the transport activity of the Na-K pump Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + Na+/out Rattus norvegicus
-
 ATP + H2O + Na+/in
-
 ?
ATP + H2O + K+/in Rattus norvegicus
-
 ADP + phosphate + K+/out
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cerebellum cerebellar granule cells Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + Na+/out
-
 Rattus norvegicus ATP + H2O + Na+/in
-
 ?
ATP + H2O + K+/in
-
 Rattus norvegicus ADP + phosphate + K+/out
-
 ?

Synonyms

Synonyms Comment Organism
Na-K-ATPase
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay condition Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay condition Rattus norvegicus