Literature summary for 7.2.2.13 extracted from

Segall, L.; Daly, S.E.; Blostein, R.
Mechanistic basis for kinetic differences between the rat alpha 1, alpha 2, and alpha 3 isoforms of the Na,K-ATPase (2001), J. Biol. Chem., 276, 31535-31541.

Search for more literature for 7.2.2.13

Cloned(Commentary)

Cloned (Comment)	Organism
expression in HeLa cells	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
Mg2+	IC50: 0.0008 mM; IC50: 0.0012 mM; IC50: 0.012 mM	Rattus norvegicus
vanadate	20fold less sensitive to vanadate than alpha1 and 3; 20 times more sensitive to vanadate than alpha2	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-
heart	adult	Rattus norvegicus	-
heart	fetal	Rattus norvegicus	-
muscle	-	Rattus norvegicus	-
nerve	-	Rattus norvegicus	-
testis	-	Rattus norvegicus	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0008	-	IC50: 0.0008 mM	Rattus norvegicus	Mg2+
0.0012	-	IC50: 0.0012 mM	Rattus norvegicus	Mg2+
0.012	-	IC50: 0.012 mM	Rattus norvegicus	Mg2+

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Release 2023.1 (January 2023)