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Literature summary for 7.2.2.12 extracted from

  • Longhin, E.; Gronberg, C.; Hu, Q.; Duelli, A.S.; Andersen, K.R.; Laursen, N.S.; Gourdon, P.
    Isolation and characterization of nanobodies against a zinc-transporting P-type ATPase (2018), Antibodies (Basel), 7, 39.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli C43 Shigella sonnei

Inhibitors

Inhibitors Comment Organism Structure
nanobody Nb9 more than 50% inhibition of the ATPase activity Shigella sonnei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Zn2+[side 1] Shigella sonnei
-
ADP + phosphate + Zn2+[side 2]
-
?
ATP + H2O + Zn2+[side 1] Shigella sonnei Ss046
-
ADP + phosphate + Zn2+[side 2]
-
?

Organism

Organism UniProt Comment Textmining
Shigella sonnei Q3YW59
-
-
Shigella sonnei Ss046 Q3YW59
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Shigella sonnei

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Zn2+[side 1]
-
Shigella sonnei ADP + phosphate + Zn2+[side 2]
-
?
ATP + H2O + Zn2+[side 1]
-
Shigella sonnei Ss046 ADP + phosphate + Zn2+[side 2]
-
?

Synonyms

Synonyms Comment Organism
zinc-transporting PIB-ATPase
-
Shigella sonnei
ZntA
-
Shigella sonnei