Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.2.2.12 extracted from

  • Janulczyk, R.; Pallon, J.; Bjorck, L.
    Identification and characterization of a Streptococcus pyogenes ABC transporter with multiple specificity for metal cations (1999), Mol. Microbiol., 34, 596-606.
    View publication on PubMed
Search for more literature for 7.2.2.12

Cloned(Commentary)

Cloned (Comment) Organism
mtsA gene Streptococcus pyogenes

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ competes with Zn2+ for the binding site Streptococcus pyogenes

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface lipoprotein, detected by antibodies Streptococcus pyogenes 9986
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 lipoprotein, SDS-PAGE Streptococcus pyogenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Cu2+/out Streptococcus pyogenes
-
 ADP + phosphate + Cu2+/in
-
 ?
ATP + H2O + Fe3+/out Streptococcus pyogenes
-
 ADP + phosphate + Fe3+/in
-
 ?
ATP + H2O + Mn2+/out Streptococcus pyogenes
-
 ADP + phosphate + Mn2+/in
-
 ?
ATP + H2O + Zn2+/out Streptococcus pyogenes
-
 ADP + phosphate + Zn2+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
-
-

Purification (Commentary)

Purification (Comment) Organism
lipoprotein MtsA Streptococcus pyogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Cu2+/out
-
 Streptococcus pyogenes ADP + phosphate + Cu2+/in
-
 ?
ATP + H2O + Fe3+/out
-
 Streptococcus pyogenes ADP + phosphate + Fe3+/in
-
 ?
ATP + H2O + Mn2+/out
-
 Streptococcus pyogenes ADP + phosphate + Mn2+/in
-
 ?
ATP + H2O + Zn2+/out
-
 Streptococcus pyogenes ADP + phosphate + Zn2+/in
-
 ?

Subunits

Subunits Comment Organism
additional information ABC-transporter Streptococcus pyogenes
additional information Lral transporter, lipoprotein, ATP-binding protein, integral membrane protein, encoded by operon mtsABC Streptococcus pyogenes