Literature summary for 7.2.1.1 extracted from

Bogachev, A.V.; Verkhovsky, M.I.
Na+-translocating NADH:quinone oxidoreductase: progress achieved and prospects of investigations (2005), Biochemistry, 70, 143-149.

Application

Application	Comment	Organism
medicine	Vibrio cholerae Na+-NQR is significant for the induction of virulence factors. Thus, this enzyme can be used as a target in the treatment or prevention of many infectious diseases	Vibrio cholerae serotype O1

Inhibitors

Inhibitors	Comment	Organism
2-heptyl-4-hydroxyquinoline N-oxide	-	Haemophilus influenzae
2-heptyl-4-hydroxyquinoline N-oxide	-	Klebsiella pneumoniae
2-heptyl-4-hydroxyquinoline N-oxide	-	Neisseria gonorrhoeae
2-heptyl-4-hydroxyquinoline N-oxide	-	Neisseria meningitidis
2-heptyl-4-hydroxyquinoline N-oxide	-	Porphyromonas gingivalis
2-heptyl-4-hydroxyquinoline N-oxide	-	Pseudomonas aeruginosa
2-heptyl-4-hydroxyquinoline N-oxide	-	Shewanella putrefaciens
2-heptyl-4-hydroxyquinoline N-oxide	-	Vibrio alginolyticus
2-heptyl-4-hydroxyquinoline N-oxide	-	Vibrio cholerae serotype O1
2-heptyl-4-hydroxyquinoline N-oxide	-	Vibrio harveyi
2-heptyl-4-hydroxyquinoline N-oxide	-	Yersinia pestis
korormicin	-	Haemophilus influenzae
korormicin	-	Klebsiella pneumoniae
korormicin	-	Neisseria gonorrhoeae
korormicin	-	Neisseria meningitidis
korormicin	-	Porphyromonas gingivalis
korormicin	-	Pseudomonas aeruginosa
korormicin	-	Shewanella putrefaciens
korormicin	-	Vibrio alginolyticus
korormicin	-	Vibrio cholerae serotype O1
korormicin	-	Vibrio harveyi
korormicin	-	Yersinia pestis

Metals/Ions

Metals/Ions	Comment	Organism
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Haemophilus influenzae
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Vibrio harveyi
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Pseudomonas aeruginosa
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Neisseria gonorrhoeae
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Neisseria meningitidis
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Klebsiella pneumoniae
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Yersinia pestis
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Porphyromonas gingivalis
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Vibrio cholerae serotype O1
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Vibrio alginolyticus
Na+	sodium ions are indispensable components of the Na+-NQR-catalyzed reaction, therefore its rate depends on concentration of Na+ and the reaction virtually does not occur in media depleted in this ion	Shewanella putrefaciens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
21500	-	1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200	Vibrio harveyi
22700	-	1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200	Vibrio harveyi
27500	-	1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200	Vibrio harveyi
45200	-	1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200	Vibrio harveyi
45400	-	1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200	Vibrio harveyi
48400	-	1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200	Vibrio harveyi

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.
additional information	Porphyromonas gingivalis	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinines. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Vibrio harveyi	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Vibrio alginolyticus	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Haemophilus influenzae	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Pseudomonas aeruginosa	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Neisseria gonorrhoeae	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Neisseria meningitidis	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Klebsiella pneumoniae	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Yersinia pestis	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Vibrio cholerae serotype O1	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
additional information	Shewanella putrefaciens	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	?	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Haemophilus influenzae	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Vibrio harveyi	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Pseudomonas aeruginosa	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Neisseria gonorrhoeae	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Neisseria meningitidis	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Klebsiella pneumoniae	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Yersinia pestis	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Porphyromonas gingivalis	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Vibrio cholerae serotype O1	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Vibrio alginolyticus	-	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	Shewanella putrefaciens	-	NAD+ + ubiquinol + 2 Na+/out	-	?

Organism

Organism	UniProt	Comment	Textmining
Haemophilus influenzae	-	-	-
Klebsiella pneumoniae	-	-	-
Neisseria gonorrhoeae	-	-	-
Neisseria meningitidis	-	-	-
Porphyromonas gingivalis	-	-	-
Pseudomonas aeruginosa	-	-	-
Shewanella putrefaciens	-	-	-
Vibrio alginolyticus	-	-	-
Vibrio cholerae serotype O1	-	-	-
Vibrio harveyi	-	-	-
Yersinia pestis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinines. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Porphyromonas gingivalis	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Vibrio harveyi	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Vibrio alginolyticus	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Haemophilus influenzae	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Pseudomonas aeruginosa	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Neisseria gonorrhoeae	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Neisseria meningitidis	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Klebsiella pneumoniae	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Yersinia pestis	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Vibrio cholerae serotype O1	?	-	?
additional information	in addition to the quinone reductase reaction the isolated enzyme can also catalyze so-called NADH dehydrogenase reaction during interaction with soluble quinones. This activity includes a single-electron reduction of soluble quinones (menadione, Q0, Q1, etc.) or some other electron acceptors (hexammineruthenium(III), ferricyanide, etc.). Similarly to the transdehydrogenase activity, the NADH dehydrogenase activity does not depend on concentration of sodium ions, is inhibited by heavy metal ions, and is insensitive to 2-heptyl-4-hydroxyquinoline N-oxide and korormicin	Shewanella putrefaciens	?	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Haemophilus influenzae	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Vibrio harveyi	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Pseudomonas aeruginosa	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Neisseria gonorrhoeae	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Neisseria meningitidis	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Klebsiella pneumoniae	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Yersinia pestis	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Porphyromonas gingivalis	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Vibrio cholerae serotype O1	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Vibrio alginolyticus	NAD+ + ubiquinol + 2 Na+/out	-	?
NADH + H+ + ubiquinone + 2 Na+/in	-	Shewanella putrefaciens	NAD+ + ubiquinol + 2 Na+/out	-	?

Subunits

Subunits	Comment	Organism
heterohexamer	-	Haemophilus influenzae
heterohexamer	-	Pseudomonas aeruginosa
heterohexamer	-	Neisseria gonorrhoeae
heterohexamer	-	Neisseria meningitidis
heterohexamer	-	Klebsiella pneumoniae
heterohexamer	-	Yersinia pestis
heterohexamer	-	Porphyromonas gingivalis
heterohexamer	-	Vibrio cholerae serotype O1
heterohexamer	-	Vibrio alginolyticus
heterohexamer	-	Shewanella putrefaciens
heterohexamer	1 * 48400 + 1 * 45400 + 1 * 27500 + 1 * 22700 + 1 * 21500 + 1 * 45200	Vibrio harveyi

Synonyms

Synonyms	Comment	Organism
Na+-NQR	-	Haemophilus influenzae
Na+-NQR	-	Vibrio harveyi
Na+-NQR	-	Pseudomonas aeruginosa
Na+-NQR	-	Neisseria gonorrhoeae
Na+-NQR	-	Neisseria meningitidis
Na+-NQR	-	Klebsiella pneumoniae
Na+-NQR	-	Yersinia pestis
Na+-NQR	-	Porphyromonas gingivalis
Na+-NQR	-	Vibrio cholerae serotype O1
Na+-NQR	-	Vibrio alginolyticus
Na+-NQR	-	Shewanella putrefaciens
Na+-translocating NADH:quinone oxidoreductase	-	Haemophilus influenzae
Na+-translocating NADH:quinone oxidoreductase	-	Vibrio harveyi
Na+-translocating NADH:quinone oxidoreductase	-	Pseudomonas aeruginosa
Na+-translocating NADH:quinone oxidoreductase	-	Neisseria gonorrhoeae
Na+-translocating NADH:quinone oxidoreductase	-	Neisseria meningitidis
Na+-translocating NADH:quinone oxidoreductase	-	Klebsiella pneumoniae
Na+-translocating NADH:quinone oxidoreductase	-	Yersinia pestis
Na+-translocating NADH:quinone oxidoreductase	-	Porphyromonas gingivalis
Na+-translocating NADH:quinone oxidoreductase	-	Vibrio cholerae serotype O1
Na+-translocating NADH:quinone oxidoreductase	-	Vibrio alginolyticus
Na+-translocating NADH:quinone oxidoreductase	-	Shewanella putrefaciens

Cofactor

Cofactor	Comment	Organism
FAD	noncovalently bound to subunit NqrF	Haemophilus influenzae
FAD	noncovalently bound to subunit NqrF	Vibrio harveyi
FAD	noncovalently bound to subunit NqrF	Pseudomonas aeruginosa
FAD	noncovalently bound to subunit NqrF	Neisseria gonorrhoeae
FAD	noncovalently bound to subunit NqrF	Neisseria meningitidis
FAD	noncovalently bound to subunit NqrF	Klebsiella pneumoniae
FAD	noncovalently bound to subunit NqrF	Yersinia pestis
FAD	noncovalently bound to subunit NqrF	Porphyromonas gingivalis
FAD	noncovalently bound to subunit NqrF	Vibrio cholerae serotype O1
FAD	noncovalently bound to subunit NqrF	Vibrio alginolyticus
FAD	noncovalently bound to subunit NqrF	Shewanella putrefaciens
FMN	covalently bound to subunits NqrB and NqrC	Haemophilus influenzae
FMN	covalently bound to subunits NqrB and NqrC	Vibrio harveyi
FMN	covalently bound to subunits NqrB and NqrC	Pseudomonas aeruginosa
FMN	covalently bound to subunits NqrB and NqrC	Neisseria gonorrhoeae
FMN	covalently bound to subunits NqrB and NqrC	Neisseria meningitidis
FMN	covalently bound to subunits NqrB and NqrC	Klebsiella pneumoniae
FMN	covalently bound to subunits NqrB and NqrC	Yersinia pestis
FMN	covalently bound to subunits NqrB and NqrC	Porphyromonas gingivalis
FMN	covalently bound to subunits NqrB and NqrC	Vibrio cholerae serotype O1
FMN	covalently bound to subunits NqrB and NqrC	Vibrio alginolyticus
FMN	covalently bound to subunits NqrB and NqrC	Shewanella putrefaciens
NADH	-	Haemophilus influenzae
NADH	-	Vibrio harveyi
NADH	-	Pseudomonas aeruginosa
NADH	-	Neisseria gonorrhoeae
NADH	-	Neisseria meningitidis
NADH	-	Klebsiella pneumoniae
NADH	-	Yersinia pestis
NADH	-	Porphyromonas gingivalis
NADH	-	Vibrio cholerae serotype O1
NADH	-	Vibrio alginolyticus
NADH	-	Shewanella putrefaciens
riboflavin	contains a noncovalently bound riboflavin	Haemophilus influenzae
riboflavin	contains a noncovalently bound riboflavin	Vibrio harveyi
riboflavin	contains a noncovalently bound riboflavin	Pseudomonas aeruginosa
riboflavin	contains a noncovalently bound riboflavin	Neisseria gonorrhoeae
riboflavin	contains a noncovalently bound riboflavin	Neisseria meningitidis
riboflavin	contains a noncovalently bound riboflavin	Klebsiella pneumoniae
riboflavin	contains a noncovalently bound riboflavin	Yersinia pestis
riboflavin	contains a noncovalently bound riboflavin	Porphyromonas gingivalis
riboflavin	contains a noncovalently bound riboflavin	Vibrio cholerae serotype O1
riboflavin	contains a noncovalently bound riboflavin	Vibrio alginolyticus
riboflavin	contains a noncovalently bound riboflavin	Shewanella putrefaciens
ubiquinone-8	-	Haemophilus influenzae
ubiquinone-8	-	Vibrio harveyi
ubiquinone-8	-	Pseudomonas aeruginosa
ubiquinone-8	-	Neisseria gonorrhoeae
ubiquinone-8	-	Neisseria meningitidis
ubiquinone-8	-	Klebsiella pneumoniae
ubiquinone-8	-	Yersinia pestis
ubiquinone-8	-	Porphyromonas gingivalis
ubiquinone-8	-	Vibrio cholerae serotype O1
ubiquinone-8	-	Vibrio alginolyticus
ubiquinone-8	-	Shewanella putrefaciens
[2Fe-2S]-center	part of subunit NqrF	Haemophilus influenzae
[2Fe-2S]-center	part of subunit NqrF	Vibrio harveyi
[2Fe-2S]-center	part of subunit NqrF	Pseudomonas aeruginosa
[2Fe-2S]-center	part of subunit NqrF	Neisseria gonorrhoeae
[2Fe-2S]-center	part of subunit NqrF	Neisseria meningitidis
[2Fe-2S]-center	part of subunit NqrF	Klebsiella pneumoniae
[2Fe-2S]-center	part of subunit NqrF	Yersinia pestis
[2Fe-2S]-center	part of subunit NqrF	Porphyromonas gingivalis
[2Fe-2S]-center	part of subunit NqrF	Vibrio cholerae serotype O1
[2Fe-2S]-center	part of subunit NqrF	Vibrio alginolyticus
[2Fe-2S]-center	part of subunit NqrF	Shewanella putrefaciens