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Literature summary for 7.1.2.2 extracted from

  • Vardanyan, Z.; Trchounian, A.
    The effects of copper (II) ions on Enterococcus hirae cell growth and the proton-translocating FoF1 ATPase activity (2010), Cell Biochem. Biophys., 57, 19-26.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ Cu2+ affects the FoF1 ATPase directly, inhibits the enzyme, causes conformational changes in the FoF1 ATPase complex, and thereby affects growth of wild-type strain ATCC9790 and of atpD mutant strain MS116, overview Enterococcus hirae

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Enterococcus hirae 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Enterococcus hirae
additional information the enzyme activity is not affected by Ni2+ at 1 mM Enterococcus hirae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + H+/out Enterococcus hirae
-
ATP + H2O + H+/in
-
?
ADP + phosphate + H+/out Enterococcus hirae ATCC 9790
-
ATP + H2O + H+/in
-
?

Organism

Organism UniProt Comment Textmining
Enterococcus hirae
-
-
-
Enterococcus hirae ATCC 9790
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture Enterococcus hirae grows well under anaerobic conditions at alkaline pH 8.0 Enterococcus hirae
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + H+/out
-
Enterococcus hirae ATP + H2O + H+/in
-
?
ADP + phosphate + H+/out
-
Enterococcus hirae ATCC 9790 ATP + H2O + H+/in
-
?

Synonyms

Synonyms Comment Organism
FoF1 ATPase
-
Enterococcus hirae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Enterococcus hirae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
assay at Enterococcus hirae

Cofactor

Cofactor Comment Organism Structure
ATP
-
Enterococcus hirae

General Information

General Information Comment Organism
additional information the atpD mutant strain MS116 expresses the FoF1 ATPase to the level as wild-type one, but it has significantly lowered H+ efflux and ATPase activity, overview Enterococcus hirae