Application | Comment | Organism |
---|---|---|
medicine | when hyperemia is induced before ischemic preconditioning, a steep increase in synthase capacity, followed by a deep decrease can be observed, hyperemia does not affect synthase capacity when applied after ischemic preconditioning, similar effects in vitro by treatment of heart biopsy samples with anoxia, which down-regulates, or high salt or high pH buffers, which up-regulates | Capra hircus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
regulatory protein IF1 | the only significant modulator of enzyme activity, 1300-1400 mM of IF1 is predicted to fully inactivate 1000 mM of synthase, both in vivo and in vitro, thus excluding significant binding numbers of non-inhibitory binding sites for IF1 in the F0 sector | Capra hircus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Capra hircus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Capra hircus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Capra hircus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + H+/in | - |
Capra hircus | ADP + phosphate + H+/out | - |
r |
Synonyms | Comment | Organism |
---|---|---|
F0F1ATP synthase | - |
Capra hircus |