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Literature summary for 7.1.1.9 extracted from

  • Tarasenko, T.N.; Pacheco, S.E.; Koenig, M.K.; Gomez-Rodriguez, J.; Kapnick, S.M.; Diaz, F.; Zerfas, P.M.; Barca, E.; Sudderth, J.; DeBerardinis, R.J.; Covian, R.; Balaban, R.S.; DiMauro, S.; McGuire, P.J.
    Cytochrome c oxidase activity is a metabolic checkpoint that regulates cell fate decisions during T cell activation and differentiation (2017), Cell Metab., 25, 1254-1268 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.1.1.9

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ferrocytochrome c + O2 + H+ Mus musculus
-
 ferricytochrome c + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
T-cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ferrocytochrome c + O2 + H+
-
 Mus musculus ferricytochrome c + H2O
-
 ?

Synonyms

Synonyms Comment Organism
COX
-
 Mus musculus
cytochrome c oxidase
-
 Mus musculus

General Information

General Information Comment Organism
malfunction T cell cytochrome c oxidase dysfunction results in apoptosis in vitro Mus musculus
physiological function cytochrome c oxidase regulates activation and proliferation in T cells through apoptosis Mus musculus