Any feedback?
Literature summary for 7.1.1.9 extracted from
- A dynamic model of nitric oxide inhibition of mitochondrial cytochrome c oxidase (2008), Biochim. Biophys. Acta, 1777, 867-876.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| NO | simple dynamic steady-state non-equilibrium model. Binding to the oxidase is always proportional to the degree of inhibition of oxygen consumption. Primary effect of NO binding to the oxidised enzyme is to convert NO to nitrite, rather than to inhibit enzyme activity | synthetic construct |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
synthetic construct | 5739 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| synthetic construct | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ferrocytochrome c + O2 + H+ | - |
synthetic construct | ferricytochrome c + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cytochrome c oxidase | - |
synthetic construct |
| cytochrome oxidase | - |
synthetic construct |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| heme a | - |
synthetic construct | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
