KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | steady-state equation for the six-state system model, substrate binding affinities under different conditions, overview | Mammalia |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial inner membrane | - |
Mammalia | 5743 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | Rieske iron-sulfur protein | Mammalia | |
Mg2+ | lowers the substrate binding affinities | Mammalia |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
quinol + 2 ferricytochrome c | Mammalia | - |
quinone + 2 ferrocytochrome c + 2 H+ | - |
? | |
ubiquinol + 2 ferricytochrome c | Mammalia | - |
ubiquinone + 2 ferrocytochrome c + 2 H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mammalia | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
quinol + 2 ferricytochrome c | - |
Mammalia | quinone + 2 ferrocytochrome c + 2 H+ | - |
? | |
ubiquinol + 2 ferricytochrome c | - |
Mammalia | ubiquinone + 2 ferrocytochrome c + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
bc1 complex | - |
Mammalia |
ubiquinol:cytochrome c oxidoreductase | - |
Mammalia |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Mammalia |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Mammalia |
General Information | Comment | Organism |
---|---|---|
additional information | model of the bc1 complex for mammalian mitochondria incorporating the major redox centers near the Qo- and Qi-site of the enzyme, and including the pH-dependent redox reactions, overview. The model consists of six distinct states characterized by the mobile electron distribution in the enzyme | Mammalia |
physiological function | the bc1 complex, is the enzyme in the respiratory chain of mitochondria responsible for the transfer reducing potential from ubiquinol to cytochrome c coupled to the movement of charge against the electrostatic potential across the mitochondrial inner membrane. The complex is also implicated in the generation of reactive oxygen species under certain conditions and is thus a contributor to cellular oxidative stress | Mammalia |