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Literature summary for 7.1.1.8 extracted from

  • Cape, J.L.; Strahan, J.R.; Lenaeus, M.J.; Yuknis, B.A.; Le, T.T.; Shepherd, J.N.; Bowman, M.K.; Kramer, D.M.
    The respiratory substrate rhodoquinol induces Q-cycle bypass reactions in the yeast cytochrome bc1 complex: mechanistic and physiological implications (2005), J. Biol. Chem., 280, 34654-34660.
    View publication on PubMed
Search for more literature for 7.1.1.8

Inhibitors

Inhibitors Comment Organism Structure
antimycin-A strong inhibition of Q-cycle bypass reactions Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics, the extent of cyt b reduction in the steady state, measurement of the reduction state of both cyt b hemes during steady state turnover, thermodynamic characterization of ubiquinol-3 and rhodoquinol-3, overview Saccharomyces cerevisiae
0.005
-
 rhodoquinol-3 pH 8.0, 23°C Saccharomyces cerevisiae
0.01
-
 decylubiquinol pH 8.0, 23°C Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Saccharomyces cerevisiae the physiological impact of a mixed Q pool in RQ-producing organisms, overview ?
-
 ?
ubiquinol + ferricytochrome c Saccharomyces cerevisiae
-
 ubiquinone + ferrocytochrome c
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
decylubiquinol + ferricytochrome c
-
 Saccharomyces cerevisiae decylubiquinone + ferrocytochrome c
-
 ?
additional information the physiological impact of a mixed Q pool in RQ-producing organisms, overview Saccharomyces cerevisiae ?
-
 ?
additional information substrate synthesis and substrate specificity, overview Saccharomyces cerevisiae ?
-
 ?
rhodoquinol-3 + 2 ferricytochrome c a substrate-induced wQ-cycle bypass reaction leading to production of superoxide Saccharomyces cerevisiae rhodoquinone-3 + 2 ferrocytochrome c + 2 H+ i.e. 2-amino-5-farnesyl-3-methoxy-6-methyl-1,4-benzoquinone ?
ubiquinol + ferricytochrome c
-
 Saccharomyces cerevisiae ubiquinone + ferrocytochrome c
-
 ?

Synonyms

Synonyms Comment Organism
Cyt bc1 complex
-
 Saccharomyces cerevisiae
cytochrome bc1 complex
-
 Saccharomyces cerevisiae
UQH2
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
23
-
 assay at Saccharomyces cerevisiae

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
76
-
 rhodoquinol-3 pH 8.0, 23°C Saccharomyces cerevisiae
143
-
 decylubiquinol pH 8.0, 23°C Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Saccharomyces cerevisiae