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Literature summary for 7.1.1.8 extracted from
- Preparation and properties of dihydroubiquinone: cytochrome c oxidoreductase (complex III) (1978), Methods Enzymol., 53, 35-40.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-alkyl-3-hydroxy-1,4-naphthoquinone | - |
Bos taurus |  |
| 2-Heptyl-4-hydroxyquinoline-N-oxide | - |
Bos taurus | |
| 2-nonyl-4-hydroxyquinoline-N-oxide | - |
Bos taurus | |
| Antimycin | - |
Bos taurus | |
| antimycin A | most potent inhibitor | Bos taurus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Iron-sulfur cluster | - |
Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Bos taurus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -70°C, complex III stable to storage and to repeated freeze-thawing | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydroubiquinone + ferricytochrome c | - |
Bos taurus | ubiquinone + ferrocytochrome c + 2 H+ | - |
? | |
| additional information | dihydroubiquinone-1 is not a suitable substrate, as it reacts nonenzymically with cytochrome c at a rapid rate | Bos taurus | ? | - |
? | |
| ubiquinol + 2 ferricytochrome c | - |
Bos taurus | ubiquinone + 2 ferrocytochrome c + 2 H+ | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome b | - |
Bos taurus | |
| cytochrome c1 | - |
Bos taurus | |
| Phospholipid | - |
Bos taurus | |
| ubiquinone | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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