Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli BW25113 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
AppBC | - |
Escherichia coli |
CydAB | - |
Escherichia coli |
cytochrome bd-I quinol oxidase | - |
Escherichia coli |
cytochrome bd-II quinol oxidase | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | loss of cytochrome bd-I oxidase subunit II (gene cydB) causes diminished respiration rates, impaired motility and enhanced acid resistance. CydB cells contain elevated heme d, particularly at low pH. The GABA/glutamate gadC antiporter is highly up-regulated in cydB cells. Eschrichia coli can compensate for the loss of cytochrome bd-I activity | Escherichia coli |
physiological function | cytochrome bd-II-mediated quinol oxidation prevents the accumulation of NADH, whereas GABA synthesis/antiport maintains the proton motive force for ATP production | Escherichia coli |