Literature summary for 7.1.1.2 extracted from

Siebels, I.; Droese, S.
Charge translocation by mitochondrial NADH ubiquinone oxidoreductase (complex I) from Yarrowia lipolytica measured on solid-supported membranes (2016), Biochem. Biophys. Res. Commun., 479, 277-282 .

Search for more literature for 7.1.1.2

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Yarrowia lipolytica	Yarrowia lipolytica

Inhibitors

Inhibitors	Comment	Organism	Structure
2-n-decyl-quinazolin-4-yl-amine	transport is completely sensitive to 2-n-decyl-quinazolin-4-yl-amine	Yarrowia lipolytica
5-(N-ethyl-N-isopropyl)amiloride	inhibits of complex I and increases the membrane conductivity	Yarrowia lipolytica
Zn2+	0.1 mM, reversible stabilization of inactive form	Yarrowia lipolytica

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Yarrowia lipolytica	16020	-

Organism

Organism	UniProt	Comment	Textmining
Yarrowia lipolytica	Q9UUU0	NUGM, 30-kDa subunit of complex I	-
Yarrowia lipolytica PIPO	Q9UUU0	NUGM, 30-kDa subunit of complex I	-

Purification (Commentary)

Purification (Comment)	Organism
solubilized by n-dodecyl-beta-D-maltoside	Yarrowia lipolytica

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
NADH + n-decylubiquinone + 5 H+[side1]	-	Yarrowia lipolytica	NAD+ + n-decylubiquinol + 4 H+[side2]	-	?
NADH + n-decylubiquinone + 5 H+[side1]	-	Yarrowia lipolytica PIPO	NAD+ + n-decylubiquinol + 4 H+[side2]	-	?

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Release 2023.1 (January 2023)