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Literature summary for 7.1.1.2 extracted from
- Purification of the NADH:ubiquinone oxidoreductase (complex I) of the respiratory chain from the inner mitochondrial membrane of Solanum tuberosum (1994), J. Biol. Chem., 269, 2263-2269.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| rotenone | strong | Solanum tuberosum |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Solanum tuberosum | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 900000 | - |
- |
Solanum tuberosum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Solanum tuberosum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Solanum tuberosum |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 11.5 | - |
activity with ubiquinone-2 | Solanum tuberosum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADH + ubiquinone | - |
Solanum tuberosum | NAD+ + ubiquinol | - |
? | |
| NADH + ubiquinone-2 | - |
Solanum tuberosum | NAD+ + reduced ubiquinol-2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | composed of at least 32 individual subunits | Solanum tuberosum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FMN | contains 0.5 mol of FMN per mol of isolated enzyme | Solanum tuberosum | |
| NADH | - |
Solanum tuberosum | |
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