Literature summary for 7.1.1.1 extracted from

Whitehead, S.J.; Rossington, K.E.; Hafiz, A.; Cotton, N.P.; Jackson, J.B.
Zinc ions selectively inhibit steps associated with binding and release of NADP(H) during turnover of proton-translocating transhydrogenase (2005), FEBS Lett., 579, 2863-2867.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli C600 and BL21(DE3) cells	Rhodospirillum rubrum

Inhibitors

Inhibitors	Comment	Organism	Structure
Cd2+	low concentrations of Cd2+ strongly inhibit revers transhydrogenation	Rhodospirillum rubrum
Zn2+	low concentrations of Zn2+ strongly inhibit revers transhydrogenation	Rhodospirillum rubrum

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Rhodospirillum rubrum	16020	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
NADPH + NAD+ + H+[side 1]	Rhodospirillum rubrum	-	NADP+ + NADH + H+[side 2]	-	r

Organism

Organism	UniProt	Comment	Textmining
Rhodospirillum rubrum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
NADPH + NAD+ + H+[side 1]	-	Rhodospirillum rubrum	NADP+ + NADH + H+[side 2]	-	r
NADPH + oxidized acetyl pyridine adenine dinucleotide + H+[side 1]	-	Rhodospirillum rubrum	NADP+ + reduced acetyl pyridine adenine dinucleotide + H+[side 2]	-	r

Synonyms

Synonyms	Comment	Organism
proton-translocating transhydrogenase	-	Rhodospirillum rubrum

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Release 2023.1 (January 2023)