Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Synechocystis sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-ethylmaleimide | binds to ChlI subunit and inhibits its ATPase activity. The ChlI-ChlD-ATP complex forms but cannot catalyse magnesium chelation. Prior incubation with MgATP2- affords protection. Full protection can also be obtained with 5 mM ATP or 5 mM ADP alone | Synechocystis sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protoporphyrin IX + Mg2+ + H2O | Synechocystis sp. | - |
ADP + phosphate + Mg-protoporphyrin IX + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Synechocystis sp. | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-protoporphyrin IX + 2 H+ | this is the first committed step of chlorophyll biosynthesis and is a branchpoint of two major routes in the tetrapyrrole pathway | Synechocystis sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protoporphyrin IX + Mg2+ + H2O | - |
Synechocystis sp. | ADP + phosphate + Mg-protoporphyrin IX + H+ | - |
? |