Crystallization (Comment) | Organism |
---|---|
crystal structures of RtcB in complex with Mn2+ alone and together with a covalently bound GMP, to 1.6 A and 2.3 A resolution, respectively. The RtcB/Mn2+ structure shows two Mn2+ ions at the active site, and an array of sulfate ions nearby that indicate the binding sites of the RNA phosphate backbone. The structure of the RtcB-GMP/Mn2+ complex reveals the detailed geometry of guanylylation of histidine 404. The enzyme's substrate-induced GTP binding site and the putative reactive RNA ends are in the vicinity of the binuclear Mn2+ active center | Pyrococcus horikoshii |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | the RtcB/Mn2+ structure shows two Mn2+ ions at the active site. The enzyme's substrate-induced GTP binding site and the putative reactive RNA ends are in the vicinity of the binuclear Mn2+ active center | Pyrococcus horikoshii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pyrococcus horikoshii | O59245 | - |
- |
Pyrococcus horikoshii DSM 12428 | O59245 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
RNA-splicing ligase | - |
Pyrococcus horikoshii |