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Literature summary for 6.5.1.8 extracted from

  • Tanaka, N.; Shuman, S.
    RtcB is the RNA ligase component of an Escherichia coli RNA repair operon (2011), J. Biol. Chem., 286, 7727-7731.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
exprression in Escherichia coli Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
gel fitlration Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P46850
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(ribonucleotide)n-2',3'-cyclophosphate + 5'-hydroxy-(ribonucleotide)m + GTP + H2O substrate mimicks the broken tRNAGlu(UUC) anticodon stem-loop generated by Kluyveromyces lactis gamma-toxin, leaving 2',3'-cyclic phosphate and 5'-OH ends Escherichia coli (ribonucleotide)n+m + GMP + diphosphate overall reaction ?
additional information RtcB seals broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester Escherichia coli ?
-
?

Subunits

Subunits Comment Organism
monomer 1 * 45000, SDS-PAGE Escherichia coli