Literature summary for 6.5.1.3 extracted from

Cherepanov, A.V.; de Vries, S.
Kinetic mechanism of the Mg2+-dependent nucleotidyl transfer catalyzed by T4 DNA and RNA ligases (2002), J. Biol. Chem., 277, 1695-1704.

Search for more literature for 6.5.1.3

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	nucleotidyl transfer Mg2+ dependent	Tequatrovirus T4

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + (ribonucleotide)n + (ribonucleotide)m	Tequatrovirus T4	-	AMP + diphosphate + (ribonucleotide)n+m	-	r

Organism

Organism	UniProt	Comment	Textmining
Tequatrovirus T4	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Tequatrovirus T4

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + (ribonucleotide)n + (ribonucleotide)m	-	Tequatrovirus T4	AMP + diphosphate + (ribonucleotide)n+m	-	r
ATP + (ribonucleotide)n + (ribonucleotide)m	only the di-magnesium-coordinated form Mg2ATP0 reacts with the enzyme, forming the covalent complex E-AMP, the reverse reaction, ATP synthesis, occurs between the mono-magnesium-coordinated diphosphate from MgP2O72- and the enzyme-MgAMP complex	Tequatrovirus T4	AMP + diphosphate + (ribonucleotide)n+m	-	r

Synonyms

Synonyms	Comment	Organism
T4 RNA ligase	-	Tequatrovirus T4

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Release 2023.1 (January 2023)