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Literature summary for 6.5.1.1 extracted from

  • Tomkinson, A.E.; Mackey, Z.B.
    Structure and function of mammalian DNA ligases (1998), Mutat. Res., 407, 1-9.
    View publication on PubMed
Search for more literature for 6.5.1.1

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
 1 * 100000 Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m Homo sapiens
-
 AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m Bos taurus
-
 AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Bos taurus
-
 indication, that DNA ligase II from bovine liver is derived from DNA ligase IIIalpha by proteolysis
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
293 cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
liver
-
 Bos taurus
-
testis
-
 Bos taurus
-
thymus
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Bos taurus AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m inable to join oligo(dT) molecules hybridized to poly(rA) Bos taurus AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m ligation of oligo(dT)/poly(dA) Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m ligation of oligo(dT)/poly(dA) and oligo(dT)/poly(rA) and oligo(rA)/poly(dT) Bos taurus AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m ligation of oligo(dT)/poly(dA) and oligo(dT)/poly(rA), unable to ligate oligo(rA)/poly(dT) Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m ligation of oligo(dT)/poly(dA) and oligo(dT)/poly(rA), unable to ligate oligo(rA)/poly(dT) Bos taurus AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 100000 Bos taurus

Synonyms

Synonyms Comment Organism
DNA ligase I
-
 Bos taurus
DNA ligase II
-
 Bos taurus
DNA ligase III
-
 Bos taurus
DNA ligase IV
-
 Homo sapiens
DNA ligase V
-
 Homo sapiens