Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.5.1.1 extracted from

  • Tom, S.; Henricksen, L.A.; Park, M.S.; Bambara, R.A.
    DNA ligase I and proliferating cell nuclear antigen form a functional complex (2001), J. Biol. Chem., 276, 24817-24825.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
proliferating cell nuclear antigen 5fold activation, proliferating cell nuclear antigen improves binding of DNA ligase I to ligation site and is responsible for the stable association of DNA ligase I to nicked duplex DNA Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m Homo sapiens
-
AMP + diphosphate + (deoxyribonucleotide)m+n
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
Homo sapiens AMP + diphosphate + (deoxyribonucleotide)m+n
-
?

Synonyms

Synonyms Comment Organism
DNA ligase I
-
Homo sapiens