Cloned (Comment) | Organism |
---|---|
expression in Sf9 insect cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
F717L | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant | Homo sapiens |
G712A | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, complements Escherichia coli lig mutant | Homo sapiens |
K724E | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant | Homo sapiens |
K727G | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant | Homo sapiens |
K727R | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant | Homo sapiens |
P718A | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, complements Escherichia coli lig mutant | Homo sapiens |
P718T | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, complements Escherichia coli lig mutant | Homo sapiens |
p719G | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant, thermolabile mutant | Homo sapiens |
R716G | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant | Homo sapiens |
R722Q | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, complements Escherichia coli lig mutant | Homo sapiens |
R722V | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, complements Escherichia coli lig mutant | Homo sapiens |
R724G | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant | Homo sapiens |
S714I | amino acid substitution within the conserved peptide of DNA ligase IIIbeta, does not complement Escherichia coli lig mutant | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | Homo sapiens | - |
AMP + diphosphate + (deoxyribonucleotide)m+n | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant DNA ligase III | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m | - |
Homo sapiens | AMP + diphosphate + (deoxyribonucleotide)m+n | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DNA ligase III | - |
Homo sapiens |