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Literature summary for 6.4.1.3 extracted from

  • Vandova, G.; OBrien, R.; Lowry, B.; Robbins, T.; Fischer, C.; Davis, R.; Khosla, C.; Harvey, C.; Hillenmeyer, M.
    Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli (2017), J. Antibiot., 70, 859-863 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis expression of the propionyl-CoA carboxylase complex from Streptomyces coelicolor supports the highest levels of heterologous polyketide production in Escherichia coli. The molar yield of 6-deoxyerythronolide B of Escherichia coli, harboring the wild-type Streptomyces coelicolor propionyl-CoA carboxylase, is 1.2% Streptomyces coelicolor

Organism

Organism UniProt Comment Textmining
Streptomyces coelicolor Q9X4K7 beta-subunit
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Synonyms

Synonyms Comment Organism
PccB
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Streptomyces coelicolor