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Literature summary for 6.4.1.2 extracted from

  • Cao, C.; Lu, S.; Kivlin, R.; Wallin, B.; Card, E.; Bagdasarian, A.; Tamakloe, T.; Chu, W.M.; Guan, K.L.; Wan, Y.
    AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytes (2008), J. Biol. Chem., 283, 28897-28908.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens regulation of ACC is necessary for maintaining the energy balance ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 isozymes ACC1 and ACC2
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein ACC is phosphorylated at Ser79 and thereby inactivated by AMP-activated protein kinase, AMPK, which is induced by UV light and H2O2. AMPK phosphorylates both isozymes of ACC, ACC1 and ACC2 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HaCaT cell
-
 Homo sapiens
-
keratinocyte
-
 Homo sapiens
-
skin
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information regulation of ACC is necessary for maintaining the energy balance Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ACC
-
 Homo sapiens